Hepatoprotective effects of Nigella sativa seed extract against acetaminophen-induced oxidative stress
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چکیده
منابع مشابه
The effects of hydroalcoholic extract of Nigella sativa seed on oxidative stress in hippocampus of STZ-induced diabetic rats
Objective: Oxidative stress plays an important role in the etiology of diabetic complications. Diabetes impairs hippocampus neurogenesis, synaptic plasticity, and learning. The aim of this study was to investigate the effects of hydroalcoholic extract of Nigella sativa seed on oxidative stress in STZ-induced diabetic rats' hippocampus. Materials and Methods: Diabetes induced by 60 mg/kg STZ, i....
متن کاملThe effects of hydroalcoholic extract of Nigella sativa seed on oxidative stress in hippocampus of STZ-induced diabetic rats
OBJECTIVE Oxidative stress plays an important role in the etiology of diabetic complications. Diabetes impairs hippocampus neurogenesis, synaptic plasticity, and learning. The aim of this study was to investigate the effects of hydroalcoholic extract of Nigella sativa seed on oxidative stress in STZ-induced diabetic rats' hippocampus. MATERIALS AND METHODS Diabetes induced by 60 mg/kg STZ, i....
متن کاملTherapeutic efficacy of Nigella sativa Linn. seed extract against CCl4 induced hepatic injury in Wistar rats.
Carbon tetrachloride (CCl4) intake damages liver. We evaluated therapeutic potential of aqueous extract of Nigella sativa seeds against CCl4 induced liver damage in rats. The hepatic damage induced by CCl4 @ 1.5 mL/kg, ip was evidenced by a significant increase in the serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), albumin, protein and urea lipid peroxidation (LPO) as we...
متن کاملAntimicrobial Activity of Nigella sativa Seed Extract (Aktiviti Antimikrob Ekstrak Nigella sativa) Nor’ AiShAh hASAN*,
Pathogenic bacterial infections have become a major health problem worldwide. New antimicrobial agents are urgently needed to overcome this problem. In this study, antibacterial activity of Nigella sativa seed extract against some pathogenic bacterial strains (Streptococcus pyogene, Pseudomonas aeruginosa, klebseilla pneumoniae and Proteus vulgaris) was evaluated. Methanol extract at the concen...
متن کاملHepatoprotective effects of Ixora parviflora extract against exhaustive exercise-induced oxidative stress in mice.
Ixora parviflora, a species of the Rubiaceae, is rich in polyphenols and flavonoids, and has been traditionally used as a folk medicine. An I. parviflora extract (IPE) has great antioxidant activity in vitro, including a scavenging effect on superoxide radicals, reducing power, and ferrous ion-chelating ability. However, whether IPE is efficacious against oxidative damage in vivo is not known. ...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Tropical Medicine
سال: 2016
ISSN: 1995-7645
DOI: 10.1016/j.apjtm.2016.01.039